ITR-100 is a brand name for capsules that contain Itraconazole 100 mg as the active ingredient. Itraconazole is an antifungal medication used to treat a wide variety of fungal infections. It works by stopping the growth of fungi by interfering with their cell membrane formation.

Uses of ITR-100 (Itraconazole 100 mg capsule):

1. Fungal Infections: It is commonly used to treat infections caused by fungi, including those affecting the lungs (e.g., Aspergillosis, Histoplasmosis) and other areas of the body, such as the skin, mouth, and nails.
2. Dermatophytosis: Itraconazole is effective in treating skin infections like Tinea pedis (athlete’s foot), Tinea cruris (jock itch), and Tinea corporis (ringworm).
3. Onychomycosis: It is frequently prescribed for nail infections (fungal infections of the toenails or fingernails).
4. Systemic Mycoses: It is used for deeper fungal infections involving internal organs such as the lungs and gastrointestinal tract.
5. Candidiasis: Itraconazole is effective against some yeast infections, including oral thrush and vaginal yeast infections caused by Candida species.

Side Effects of ITR-100 (Itraconazole 100 mg capsule):

Though effective, Itraconazole can cause side effects in some individuals. These may range from mild to severe, and not everyone will experience all of them.

Common Side Effects:

1. Nausea and Vomiting
2. Diarrhea
3. Abdominal Pain
4. Headache
5. Dizziness
6. Fatigue

Serious Side Effects (Require immediate medical attention):

1. Liver Issues: Itraconazole can cause liver toxicity. Symptoms may include:
   • Yellowing of the skin or eyes (jaundice)
   • Dark urine
   • Pale stools
   • Severe stomach pain
2. Heart Issues: Long-term use may cause or worsen heart conditions, especially in patients with pre-existing heart problems. Symptoms may include:
   • Shortness of breath
   • Swelling in ankles or feet
   • Unusual tiredness
3. Hearing Loss: Rarely, Itraconazole has been associated with temporary or permanent hearing loss.
4. Allergic Reactions: Symptoms of a severe allergic reaction include:
   • Rash or itching
   • Difficulty breathing
   • Swelling of the face, lips, tongue, or throat
5. Severe Skin Reactions: Including Stevens-Johnson syndrome or toxic epidermal necrolysis, both of which can be life-threatening.
6. Hypersensitivity to Sunlight: In some cases, Itraconazole can make the skin more sensitive to sunlight.

Precautions and Interactions:

• Liver Function: Regular liver function tests may be needed, especially if used for long durations.
• Heart Conditions: Patients with heart issues (congestive heart failure) should be cautious when using Itraconazole.
• Drug Interactions: Itraconazole can interact with many medications, including:
  • Statins (cholesterol-lowering drugs)
  • Certain antibiotics
  • Anti-arrhythmics
  • Anticoagulants (Warfarin)

Patients should inform their healthcare provider of any medications they are taking, including over-the-counter drugs and supplements.

Conclusion:

ITR-100 containing Itraconazole 100 mg is an effective antifungal treatment but comes with potential side effects. It is important to use this medication under the guidance of a healthcare provider and report any unusual symptoms immediately. Regular monitoring may be required during treatment, especially in patients with pre-existing liver or heart conditions.